JNJ-38893777 sulfate( JNJ38893777 )

Catalog No. M16803 CAS No. 951135-07-2

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Product Name

JNJ-38893777 sulfate
Note

Research use only, not for human use.
Brief Description

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.
Description

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.Pain Phase 1 Clinical.
In Vitro

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In Vivo

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Synonyms

JNJ38893777
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRP/TRPV Channel
Research Area

Neurological Disease
Indication

Pain

CAS Number

951135-07-2
Formula Weight

634.598
Molecular Formula

C26H28F6N6O4S
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine sulfate

1. Manitpisitkul P, et al. Clin Drug Investig. 2015 Jun;35(6):353-63. 2. Meents JE, et al. J Headache Pain. 2015;16:57.

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